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Desarrollo de un chip MD económico para filiación, diagnóstico de enfermedades, detección de caracteres de importancia económica, selección genómica en PRE…

EQUIGENOM Operational Group: Development of a cost-effective MD chip for gene identification, disease diagnosis, detection of economically important traits, and genomic selection in PRE.

  • Type Operational group
  • Execution 2022 -2025
  • Assigned Budget 570.505,34 €
  • Scope Supraautonómico
  • Autonomous community Andalucía; Aragón; Madrid, Comunidad de
  • Main source of financing PEPAC 2014-2020
  • Project website https://goequigenom.com
Description

Innovative application of an economical medium-density (MD) chip for the PRE that simultaneously allows the control of parentage, the early diagnosis of hereditary diseases (including those particular and specific to the PRE breed, such as cat neck among others) and chromosomal diseases, the detection of molecular markers related to traits of economic importance and the development of genomic selection in the PRE, which will be complemented by the development of a robust and easy-to-use digital tool, which integrates genetic information (from the improvement program) and/or genomic information (generated by the chip) of each animal, allowing its use in a quick and easy way to interpret for the farmer, centralizing all the information of the same animal in a single accessible digital file that helps them make improvement and crossbreeding decisions that allow higher and faster genetic progress and the detection and control of hereditary diseases, avoiding considerable economic expense as well as anticipating future problems and economic losses; with the consequent economic benefit of the farm.

Objectives
  • Obtaining an economical medium density (MD) chip for the affiliation and genotyping of diseases and other characters of economic importance.
  • Development of a genomic assessment system in the PRE.
  • Development of a new digital tool accessible to farmers to enable them to interpret the results obtained from the chip.
Results
  • Selection of the reference population and genetic markers for diseases, Design and production of the medium-density chip and validation in the PRE.
  • Development of genomic assessment models for the different PRE selection criteria.
  • Design and development of the LG digital web tool and LG app, as well as its dissemination in the Spanish equine sector.
Contact information
  • Coordinator/entity name: Royal National Association of Purebred Spanish Horse Breeders (ANCCE)
  • Coordinator/entity email: direccion@lgancce.com
Collaborators
  • Federación española de Asociaciónes de criadores de caballos (FEACC)
  • Real federación hípica española (RFHE)
  • Sociedad española de equinotecnia
Beneficiaries
  • Real asociación nacional de criadores de caballos de pura raza española (ANCCE)
  • Real federación española de Asociaciónes de ganado selecto (RFEAGAS)
  • Life technologies S.A
Outsourced
  • Universidad de Sevilla
  • Universidad de Córdoba (UCo)
  • Esmedagro SL